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KMID : 1024220150300010003
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Environmental Health and Toxicology : EHT
2015 Volume.30 No. 1 p.3 ~ p.3
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Size-dependent toxicity of silver nanoparticles to Glyptotendipes tokunagai
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:Choi Seon-A
:Kim So-Youn/:Bae Yeon-Jae/:Park June-Woo/:Jung Jin-Ho
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Abstract
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Objectives: This study aims to evaluate the size-dependent toxicity of spherical silver nanoparticles (Ag NPs) to an endemic benthic organism, Glyptotendipes tokunagai.
Methods: Ag nanoparticles of three nominal sizes (50, 100, and 150 nm) capped with polyvinyl pyrrolidone (PVP-Ag NPs) were used. Their physicochemical properties, acute toxicity (48 hours), and bioaccumulation were measured using third instar larvae of G. tokunagai.
Results: The aggregation and dissolution of PVP-Ag NPs increased with exposure time and concentration, respectively, particularly for 50 nm PVP-Ag NPs. However, the dissolved concentration of Ag ions was not significant compared with the median lethal concentration value for AgNO3 (3.51 mg/L). The acute toxicity of PVP-Ag NPs was highest for the smallest particles (50 nm), whereas bioaccumulation was greatest for the largest particles (150 nm). However, larger PVP-Ag NPs were absorbed and excreted rapidly, resulting in shorter stays in G. tokunagai than the smaller ones.
Conclusions: The size of PVP-Ag NPs significantly affects their acute toxicity to G. tokunagai. In particular, smaller PVP-Ag NPs have a higher solubility and stay longer in the body of G. tokunagai, resulting in higher toxicity than larger PVP-Ag NPs.
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KEYWORD
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Bioacummulation, Chironomus, Nanotoxicity, Nanoparticle, Particles size
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